Terms You Want to Know E - N
- Hamartin: A protein made by the TSC1 gene. Hamartin and tuberin, a protein produced by the TSC2 gene, function together in cells to regulate cell growth and prevent the overgrowth of cells into tumors.
- Hemoptysis: The coughing up of blood or bloody sputum from the lungs or airway. It may be either self-limiting or recurrent.
- Lymphangioleiomyomatosis (LAM): A rare, fatal lung disease that affects women in their childbearing years. In LAM, abnormal smooth muscle-like cells proliferate in the lungs, pulmonary airway, parenchyma, lymphatics, and blood vessels, ultimately leading to respiratory failure.
- mTOR (mammalian target of rapamycin): A protein that inhibits the process by which cells break down their own components to recycle the building blocks from which they are made. The mTOR pathway plays a fundamental role in cell growth via the regulation of protein synthesis.
- NIH Roadmap for Medical Research: A set of initiatives developed by the U.S. National Institutes of Health aimed at accelerating medical research. The Roadmap identifies the most compelling opportunities in three arenas: new pathways to discovery, research teams of the future, and reengineering the clinical research enterprise.
